4,839 research outputs found
Control system integration
This lecture begins with a definition of an accelerator control system, and then reviews the control system architectures that have been deployed at the larger accelerator facilities. This discussion naturally leads to identification of the major subsystems and their interfaces. We shall explore general strategies for integrating intelligent devices and signal processing subsystems based on gate arrays and programmable DSPs. The following topics will also be covered: physical packaging; timing and synchronization; local and global communication technologies; interfacing to machine protection systems; remote debugging; configuration management and source code control; and integration of commercial software tools. Several practical realizations will be presented
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Interfacing to accelerator instrumentation
As the sensory system for an accelerator, the beam instrumentation provides a tremendous amount of diagnostic information. Access to this information can vary from periodic spot checks by operators to high bandwidth data acquisition during studies. In this paper, example applications will illustrate the requirements on interfaces between the control system and the instrumentation hardware. A survey of the major accelerator facilities will identify the most popular interface standards. The impact of developments such as isochronous protocols and embedded digital signal processing will also be discussed
Competing Harvesting Strategies In A Simulated Population Under Uncertainty
We present a case study of the use of simulation modelling to develop and test strategies for managing populations under uncertainty. Strategies that meet a stock conservation criterion under a base case scenario are subjected to a set of robustness trials, including biased and highly variable abundance estimates and poaching. Strategy performance is assessed with respect to a conservation criterion, the revenues achieved and their variability. Strategies that harvest heavily, even when the population is apparently very large, perform badly in the robustness trials. Setting a threshold below which harvesting does not take place, and above which all individuals are harvested, does not provide effective protection against over-harvesting. Strategies that rely on population growth rates rather than estimates of population size are more robust to biased estimates. The strategies that are most robust to uncertainty are simple, involving harvesting a relatively small proportion of the population each year. The simulation modelling approach to exploring harvesting strategies is suggested as a useful tool for the assessment of the performance of competing strategies under uncertainty
A Pilot Study on Cannabidiol (CBD) and Eccentric Exercise: Impact on Inflammation, Performance, and Pain
International Journal of Exercise Science 16(2): 109-117, 2023. Cannabidiol (CBD) is a non-psychoactive cannabinoid purported to reduce symptoms of discomfort. Individuals are now using CBD to treat symptoms of multiple sclerosis, seizures, and chronic pain. Animal models indicate that CBD may be effective at reducing inflammation post fatiguing exercise. However, little evidence is available to evaluate these findings in humans. Therefore, the purpose of this investigation was to evaluate the impact of two doses of CBD oil on inflammation (IL-6), performance, and pain after an eccentric loading protocol. Participants (n = 4) participated in three conditions (placebo, low dose, and high dose), in this randomized, counterbalanced design. Each condition took 72 hours to complete, with a 1-week washout period between conditions. At the beginning of each week, participants were subjected to a loading protocol of six sets of ten eccentric only repetitions in the single-arm bicep curl. Participants consumed capsules of either a placebo, low dose (2mg/kg) or high dose (10mg/kg) of CBD oil immediately following the session and continued every twelve hours for 48 hours. Venipunctures were taken before exercise and repeated at 24, 48, and 72 hours post exercise. Blood samples were centrifuged for 15 minutes in gel and lithium heparin vacutainers. Plasma was separated from cells and stored at -80° until analysis. Samples were analyzed using an immunometric assay for IL-6 (ELISA). Data were analyzed using a three (condition) by four (time) repeated measure ANOVA. There were no differences in inflammation between conditions (F(2,6) = 0.726, p = 0.522, np2 = 0.195) or across time (F(3,9) = 0.752, p = 0.548, np2 = 0.200), handgrip strength between conditions (F(2,6) = 0.542, p = 0.607, np2 = .153) or across time (F(3,9) = 2.235, p = .153, np2 = .427), or bicep curl strength between conditions (F(2,6) = 0.675, p = 0.554, np2 = .184) or across time (F(3,9) = 3.513, p = .150, np2 = .539). There were no differences in pain between conditions (F(2,6) = 0.495, p = 0.633, np2 = .142), but there was a difference across time (F(3,9) = 7.028, p = .010, np2 = .701). There were no significant interactions to note. Although there was no statistical significance between conditions (likely due to the low sample size), there was a visible increase in IL-6 48 (4.88 ± 6.53) and 72 hours (3.12 ± 4.26) post exercise in the placebo condition which was not observed in the low (48: 0.35 ± 2.22; 72: 1.34 ± 5.6) and high dose condition (48: 1.34 ± 1.34; 72: -0.79 ± 5.34). Future investigations should consider implementing eccentric resistance training across a larger portion of the body to improve ecological validity of the exercise. A larger sample would reduce risk of researchers committing a type II statistical error and give strength to detecting differences between conditions
Evidence of Rapid Phenocryst Growth of Olivine During Ascent in Basalts From the Big Pine Volcanic Field: Application of OlivineâMelt Thermometry and Hygrometry at the Liquidus
The Quaternary Big Pine (BP) volcanic field in eastern California is notable for the occurrence of mantle xenoliths in several flows. This points to rapid ascent of basalt through the crust and precludes prolonged storage in a crustal reservoir. In this study, the hypothesis of phenocryst growth during ascent is tested for several basalts (13â7 wt% MgO) and shown to be viable. Phenocrysts of olivine and clinopyroxene frequently display diffusionâlimited growth textures, and clinopyroxene compositions are consistent with polybaric crystallization. When the most Mgârich olivine in each sample is paired with the wholeârock composition, resulting Fe2+âMgKD(olivineâmelt) values (0.31â0.36) match those calculated from literature models (0.32â0.36). Application of a Mgâ and a Niâbased olivineâmelt thermometer from the literature, both calibrated on the same experimental data set, leads to two sets of temperatures that vary linearly with wholeârock MgO wt%. Because the Ni thermometer is independent of water content, it provides the actual temperature at the onset of olivine crystallization (1247â1097°C), whereas the Mg thermometer gives the temperature under anhydrous conditions and thus allows ÎT (=TMg â TNi = depression of liquidus due to water) to be obtained. The average ÎT for all samples is ~59°C, which is consistent with analyzed water contents of 1.5â3.0 wt% in olivineâhosted melt inclusions from the literature. Because the application of olivineâmelt thermometry/hygrometry at the liquidus only requires microprobe analyses of olivine combined with wholeârock compositions, it can be used to obtain large global data sets of the temperature and water contents of basalts from different tectonic settings.Plain Language SummaryBasaltic lavas are a window into their mantle source regions, which is why it is important to determine their temperatures and water contents. In this study, a new approach that allows these two parameters to be quantified is demonstrated for basalts from the Big Pine volcanic field, CA. They were targeted because many contain chunks of dense mantle rocks, which precludes storage in a crustal magma chamber and points to direct ascent from the mantle to the surface along fractures. Two hypotheses are proposed, tested, and shown to be viable in this study: (1) olivine crystallized in the basalts during ascent, and (2) the most Mgârich olivine analyzed in each basalt represents the first olivine to grow during ascent. This enables the most Mgârich olivine to be paired with the wholeârock composition in the application of olivineâmelt thermometry and hygrometry. The results match those from published, independent studies. The success of this approach paves the way for the attainment of large, highâquality data sets for basalts from a wide variety of tectonic settings. This, in turn, may allow global variations in mantle temperature and volatile content to be mapped in greater detail and better understood.Key PointsRapid phenocryst growth occurs during ascent in Mgârich basalts (some carry mantle xenoliths) from the Big Pine volcanic field, CAThe most Mgârich olivine can be paired with the wholeârock composition to apply olivineâmelt thermometry/hygrometry at the liquidusLarge, highâquality data sets on the temperature and water content of basalts from various tectonic settings can be obtained by this methodPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/163434/3/ggge22329-sup-0001-2020GC009264-SI.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/163434/2/ggge22329.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/163434/1/ggge22329_am.pd
Using gamma+jets Production to Calibrate the Standard Model Z(nunu)+jets Background to New Physics Processes at the LHC
The irreducible background from Z(nunu)+jets, to beyond the Standard Model
searches at the LHC, can be calibrated using gamma+jets data. The method
utilises the fact that at high vector boson pT, the event kinematics are the
same for the two processes and the cross sections differ mainly due to the
boson-quark couplings. The method relies on a precise prediction from theory of
the Z/gamma cross section ratio at high pT, which should be insensitive to
effects from full event simulation. We study the Z/gamma ratio for final states
involving 1, 2 and 3 hadronic jets, using both the leading-order parton shower
Monte Carlo program Pythia8 and a leading-order matrix element program Gambos.
This enables us both to understand the underlying parton dynamics in both
processes, and to quantify the theoretical systematic uncertainties in the
ratio predictions. Using a typical set of experimental cuts, we estimate the
net theoretical uncertainty in the ratio to be of order 7%, when obtained from
a Monte Carlo program using multiparton matrix-elements for the hard process.
Uncertainties associated with full event simulation are found to be small. The
results indicate that an overall accuracy of the method, excluding statistical
errors, of order 10% should be possible.Comment: 22 pages, 14 figures; Accepted for publication by JHE
A point process framework for modeling electrical stimulation of the auditory nerve
Model-based studies of auditory nerve responses to electrical stimulation can
provide insight into the functioning of cochlear implants. Ideally, these
studies can identify limitations in sound processing strategies and lead to
improved methods for providing sound information to cochlear implant users. To
accomplish this, models must accurately describe auditory nerve spiking while
avoiding excessive complexity that would preclude large-scale simulations of
populations of auditory nerve fibers and obscure insight into the mechanisms
that influence neural encoding of sound information. In this spirit, we develop
a point process model of the auditory nerve that provides a compact and
accurate description of neural responses to electric stimulation. Inspired by
the framework of generalized linear models, the proposed model consists of a
cascade of linear and nonlinear stages. We show how each of these stages can be
associated with biophysical mechanisms and related to models of neuronal
dynamics. Moreover, we derive a semi-analytical procedure that uniquely
determines each parameter in the model on the basis of fundamental statistics
from recordings of single fiber responses to electric stimulation, including
threshold, relative spread, jitter, and chronaxie. The model also accounts for
refractory and summation effects that influence the responses of auditory nerve
fibers to high pulse rate stimulation. Throughout, we compare model predictions
to published physiological data and explain differences in auditory nerve
responses to high and low pulse rate stimulation. We close by performing an
ideal observer analysis of simulated spike trains in response to sinusoidally
amplitude modulated stimuli and find that carrier pulse rate does not affect
modulation detection thresholds.Comment: 1 title page, 27 manuscript pages, 14 figures, 1 table, 1 appendi
Solar Neutron Events of October-November 2003
During the period when the Sun was intensely active on October-November 2003,
two remarkable solar neutron events were observed by the ground-based neutron
monitors. On October 28, 2003, in association with an X17.2 large flare, solar
neutrons were detected with high statistical significance (6.4 sigma) by the
neutron monitor at Tsumeb, Namibia. On November 4, 2003, in association with an
X28 class flare, relativistic solar neutrons were observed by the neutron
monitors at Haleakala in Hawaii and Mexico City, and by the solar neutron
telescope at Mauna Kea in Hawaii simultaneously. Clear excesses were observed
at the same time by these detectors, with the significance calculated as 7.5
sigma for Haleakala, and 5.2 sigma for Mexico City. The detector onboard the
INTEGRAL satellite observed a high flux of hard X-rays and gamma-rays at the
same time in these events. By using the time profiles of the gamma-ray lines,
we can explain the time profile of the neutron monitor. It appears that
neutrons were produced at the same time as the gamma-ray emission.Comment: 35 pages, 21 figures, accepted for publication in Ap
Discrete breathers in dc biased Josephson-junction arrays
We propose a method to excite and detect a rotor localized mode
(rotobreather) in a Josephson-junction array biased by dc currents. In our
numerical studies of the dynamics we have used experimentally realizable
parameters and included self-inductances. We have uncovered two families of
rotobreathers. Both types are stable under thermal fluctuations and exist for a
broad range of array parameters and sizes including arrays as small as a single
plaquette. We suggest a single Josephson-junction plaquette as an ideal system
to experimentally investigate these solutions.Comment: 5 pages, 5 figure, to appear June 1, 1999 in PR
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